STUDY PROTOCOL: A MIXED-METHODS STUDY TO EVALUATE WHICH HEALTH VISITING MODELS IN ENGLAND ARE MOST PROMISING FOR MITIGATING THE HARMS OF ADVERSE CHILDHOOD EXPERIENCES

Introduction Exposure to adverse childhood experiences (ACEs) is associated with poorer health outcomes throughout life.In England, health visiting is a long-standing, nationally implemented service that aims to prevent and mitigate the impact of adversity in early childhood, including for children exposed to ACEs.A range of health visiting service

The state of the art ion mobility quadrupole time of flight (IM-QTOF) mass spectrometer coupled with ultra-high performance liquid chromatography (UHPLC) can offer four-dimensional information supporting the comprehensive multicomponent characterization of traditional Chinese medicine (TCM).Compound Xueshuantong Capsule (CXC) is a four-component Ch

Abstract Background Evolution of splice sites is a well-known phenomenon that results in transcript diversity during human evolution.Many novel splice sites are derived from repetitive elements and may not contribute to protein products.Here, we analyzed annotated human protein-coding exons and identified human-specific splice sites that arose afte

We propose an application-oriented nonlinear control approach for centrifugal compressors, tailored to meet requirements of industrial applications such as variable process demands and adherence to operational constraints, for instance surge avoidance.Our compressor model modifies an approach of Gravdahl and Egeland by including key features of an

Facial emotion recognition (FER) is rapidly advancing, with significant applications in healthcare, human-computer interactions, and biometric security, driven by recent advances in artificial intelligence (AI), computer vision, and deep learning.In recent studies, various algorithms have encountered several challenges such as data scarcity, low-re